UCSF Responds to Comparative Effectiveness Research (CER) Opportunities

Comparative Effectiveness Research (CER) seeks to determine which medical interventions and strategies work best, for whom, and under what circumstances.

  • See the National Institutes of Health (NIH) definition of CER >>
  • Read more about what UCSF is doing

Funding Opportunities

The American Recovery and Reinvestment Act (ARRA) of 2009 appropriated $1.1B for CER over two years. Of this amount, $300M will be distributed by the Agency for Healthcare Research and Quality (AHRQ), $400M by the National Institutes of Health (NIH) and the remaining $400M by the Department of Health and Human Services (DHHS). View announcements:

The AHRQ spending plan focuses on new research, patient registries, infrastructure and dissemination. Learn more about grant categories >>

For the time being, the AHRQ will focus on the same 14 priority conditions designated earlier by the HHS Secretary under the Medicare Modernization Act. The priority conditions were selected based on their high interest for Medicare, Medicaid, and the Children’s Health Insurance Program (CHIP). Learn about priority conditions >>

Requests for Applications

GrantDetailsDeadlines
AHRQ Patient Centered Outcomes Research (PCOR) Institutional Mentored Career Development Program (K12). The purpose of this solicitation is to support the career development of post-doctoral and junior research and clinical doctorate faculty scholars in comparative effectiveness research methods, applied to patient-centered outcomes. Agency: AHRQ
RFA-HS-13-008
Letter of Intent: June 7, 2013
Application: 5:00 PM July 17, 2013, local time of applicant organization.
The National Patient-Centered Clinical Research Network: Patient-Powered Research Networks (PPRN)—Phase One PCORI will provide $12 million to fund up to 18 new or existing Patient-Powered Research Networks with the goal of helping them become scalable, reusable, and sustainable networks for research. Agency: PCORI

Up to $12M 		Letter of Intent: 5:00 PM (EST), Wednesday, June 19, 2013
Application: 5:00 PM (EST) Friday, September 27, 2013.
The National Patient-Centered Clinical Research Network: Clinical Data Research Networks (CDRN)—Phase One PCORI will provide $56 million to support eight new or existing Clinical Data Research Networks. The goal of these CDRNs is to conduct randomized comparative effectiveness studies using data from clinical practices. Agency: PCORI

Up to $56M 		Letter of Intent: 5:00 PM (EST), Wednesday, June 19, 2013
Application: 5:00 PM (EST) Friday, September 27, 2013.
AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Clinical Investigator Award (K08) The primary purpose of the AHRQ PCOR Mentored Clinical Investigator Award (K08) program is to prepare qualified individuals for careers utilizing complex comparative effectiveness research (CER) methods to clinical and health systems PCOR issues, involving stakeholders, as appropriate, in the design, execution,and dissemination of the research. Agency: AHRQ
PAR-13-180
 Application: Standard dates apply, by 5:00 PM local time of applicant organization.
AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Research Scientist Development Award (K01) The primary purpose of this award is to prepare qualified individuals for careers utilizing complex comparative effectiveness research (CER) methods to clinical and health systems PCOR issues, involving stakeholders, as appropriate, in the design, execution,and dissemination of the research. Agency: AHRQ
PAR-13-181
 Application: Standard dates apply, by 5:00 PM local time of applicant organization.
AHRQ Mentored Career Enhancement Award in Patient Centered Outcomes Research (PCOR) for Mid-Career and Senior Investigators (K18) Targeting established mid-career and senior investigators who are interested in developing new skills in comparative effectiveness research methodology and applying these methods to patient-centered outcome research (PCOR). Agency: AHRQ
PAR-12-115
$275,000/year, 2 years max 		Application: May 2, 2012, December 18, 2012, December 18, 2013, December 18, 2014
Translational Scholar Career Awards in Pharmacogenomics and Personalized Medicine (K23) Providing salary and protected time (up to five years for this award) to support the career development of investigators who have made a commitment to focus their research endeavors on patient-oriented research. Agencies: NCRR, NCI, NIDA, NIGMS, NINR, NCATS
PA-11-009
$200,000/year, 3 years max 		Application: Standard dates apply
Infrastructure Development Program in Patient-Centered Outcomes Research (PCOR) (R24) Supports applications from organizations that propose to improve health outcomes by developing and disseminating evidence-based information to patients, clinicians, policy makers, and health care administrators, responding to their expressed needs about which clinical and health system design interventions are most effective for which patients under specific circumstances. Agencies: AHRQ
PA-12-114
$1,000,000/year, 5 years
Eligibility: Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the PD/PI is invited to work with his/her organization to develop an application for support. A minimum time commitment of 1.8 calendar months (i.e. 15%) annual effort is required from the PD/PI. 		Application:
June 19, 2012, Dec 19, 2012, Dec 19, 2013, Dec 19, 2014
Partnerships in Implementing Patient Safety II (R18) To support Research Demonstration and Dissemination (R18) grant applications from organizations that will implement safe practice interventions that demonstrate evidence of reducing or eliminating medical errors, risks, hazards, and harms associated with the process of health care. Agencies: DHHS, AHRQ
PAR-10-022
$600,000/2 years
Eligibility: Project Directors/Principal Investigators at listed institutions/organizations		 Standard dates apply
Learn more

View the complete list of opportunities

Announcements

  • New Methods in Statistical Methodology to decrease potential bias and confounding in Comparative Effectiveness Research — Mark van der Laan, Professor of Biostatistics at UC Berkeley, developed these methods that combine the application of super learning (SL) and targeted maximum likelihood estimation (TMLE). He is looking to apply these methods by partnering with CER researchers and grant applicants with large clinical databases. Learn more.
  • Suspension of Grants Funding Appeals Process

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UCSF Steering Committee

A Steering Committee charged with coordinating and supporting Comparative Effectiveness Research (CER) at UCSF will meet bi-monthly and may organize a meeting of all faculty interested in CER late fall 2009.

Steering Committee Members >>

Stay Informed

Contact us if you would like to be informed of Comparative Effectiveness Research funding opportunities and potential collaborations.

See previous announcements sent to the CER distribution list:

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