Skip to main content Skip to navigation
UCSF
  • University of California, San Francisco
  • About UCSF
  • Search UCSF
  • UCSF Medical Center
  • CTSICTSI at UCSF
  • ServicesServices for Researchers
  • ProfilesUCSF Profiles
Accelerate
Access CTSI services to enable research

Powered by CTSI

 

CTSI Main Navigation

  • Home
  • About
    • Overview: About Accelerate
    • News, Events & Deadlines
    • Glossary & Acronyms
    • Contact Us
  • Research Resources
    • Overview
    • Request a Consultation
    • Search Core Facilities & Services
    • Clinical Research Services
      • CRS Home: Services & Facilities
      • CRS Facilities
      • Sample Processing Core Laboratories
      • Guidelines & Application Process
      • Download CRS Forms
      • Contact Information
      • CRS FAQ
      • Advisory Committee Schedule
      • Publications
      • Resources for Grant Applications
      • Community: Information for Participants
      • Industry Guidelines and Rates
    • UCSF Participant Recruitment Service
    • UCSF Profiles
    • Work with Industry
    • T1 Translational Research
    • Work with Community
      • Work with Community
      • Work with Community FAQ
      • Guides and Resource Manuals
      • Articles, Reports, and Books
      • Presentations and Tools
      • Community Engagement eNews
    • Informatics Resources
    • Comparative Effectiveness Research (CER) Resources
    • Work with Large Datasets
    • mHealth Research Resources
    • UCSF International Database
    • Ask a Question
  • Training & Advancement
    • Overview
    • UCSF Opportunities Matrix
    • K Proposal Library
    • T32 Proposal Library
    • Career Advancement Library
    • Training in Clinical Research (TICR) Program
    • CTSI Online Education
    • Training in Implementation Science
    • Mentor Development Course
    • Clinical & Translational Research Fellowships
    • Faculty Opportunities
      • Faculty Opportunities
      • Junior Faculty Mentoring Program
      • Traveling Ambassador Program
    • Resident Opportunities
    • Trainee Opportunities
      • Trainee Opportunities
      • Clinical Research Services Training
      • Pre-Health Undergraduate Program (PUP)
  • Funding
    • Overview
    • Resource Allocation Program (RAP)
    • K Proposal Library
    • T32 Proposal Library
    • Faculty Career Development Awards
    • Postdoctoral Funding
    • Resident Funding
    • T1 Translational Catalyst Award
    • Community-Engaged and T2 Research Funding
    • Comparative Effectiveness Research (CER) Funding
      • CER Active Funding Opportunities
      • CER Inactive Funding Opportunities
    • Informatics Funding
  • Collaboration Tools
    • Overview
    • UCSF Profiles
    • Open Forums
    • Research Blogs
  • For Community Partners
    • Overview
    • Request a Consultation
    • Linkage Service
    • Training
    • Collaborative Research Network
    • Working with Researchers
Home breadcrumb Funding breadcrumb

UCSF Responds to Comparative Effectiveness Research (CER) Opportunities

Comparative Effectiveness Research (CER) seeks to determine which medical interventions and strategies work best, for whom, and under what circumstances.

  • See the National Institutes of Health (NIH) definition of CER >>
    Comparative effectiveness research is the conduct and synthesis of research comparing the benefits and harms of different interventions and strategies to prevent, diagnose, treat and monitor health conditions in "real world" settings. The purpose of this research is to improve health outcomes by developing and disseminating evidence-based information to patients, clinicians, and other decision-makers, responding to their expressed needs, about which interventions are most effective for which patients under specific circumstances. To provide this information, comparative effectiveness research must assess a comprehensive array of health-related outcomes for diverse patient populations and sub-groups. Defined interventions compared may include medications, procedures, medical and assistive devices and technologies, diagnostic testing, behavioral change, and delivery system strategies. This research necessitates the development, expansion, and use of a variety of data sources and methods to assess comparative effectiveness and actively disseminate the results.
  • Read more about what UCSF is doing

Funding Opportunities

The American Recovery and Reinvestment Act (ARRA) of 2009 appropriated $1.1B for CER over two years. Of this amount, $300M will be distributed by the Agency for Healthcare Research and Quality (AHRQ), $400M by the National Institutes of Health (NIH) and the remaining $400M by the Department of Health and Human Services (DHHS). View announcements:

  • Agency for Healthcare Research and Quality (AHRQ)
  • National Institutes of Health (NIH)
  • Department of Health and Human Services (DHHS)
  • UCSF Responds to American Recovery and Reinvestment Act (ARRA)

The AHRQ spending plan focuses on new research, patient registries, infrastructure and dissemination. Learn more about grant categories >>

New Grants ($198.5 million):

  • $148 million for evidence generation, including prospective studies and patient registries.
  • $100 million for the Clinical and Health Outcomes Initiative in Comparative Effectiveness (CHOICE), a new national effort to establish a series of prospective pragmatic clinical comparative effectiveness studies that measure the benefits treatments produce in routine clinical practice. This will include novel study designs focusing on real-world and under-represented populations (children, elderly, racial and ethnic minorities, and other understudied populations).
  • $48 million for the establishment or enhancement of national patient registries that can be used for researching the longitudinal effects of different interventions and collecting data on under-represented populations.
  • $29.5 million to support innovative translation and dissemination grants.
  • $20 million to support training and career development.
  • $1 million for other grants.

New Contracts ($19.5 million)

  • $9.5 million to establish an infrastructure to identify new issues for comparative effectiveness research.
  • $10 million to establish a citizen’s forum to engage stakeholders and to expand and standardize public involvement in the federal comparative effectiveness research program.

Expand Existing Contracts ($79 million):

  • $50 million for evidence synthesis.
  • $24 million for evidence generation.
  • $5 million for translation and dissemination.

Administration ($3 million)

  • $3 million for salary and benefits for new AHRQ staff to administer the CER program.

For the time being, the AHRQ will focus on the same 14 priority conditions designated earlier by the HHS Secretary under the Medicare Modernization Act. The priority conditions were selected based on their high interest for Medicare, Medicaid, and the Children’s Health Insurance Program (CHIP). Learn about priority conditions >>

  • Arthritis and non-traumatic joint disorders
  • Cancer
  • Cardiovascular disease, including stroke and hypertension
  • Dementia and other brain and nerve conditions, including Alzheimer’s Disease
  • Depression and other mental health disorders
  • Developmental delays, attention-deficit hyperactivity disorder, and autism
  • Diabetes mellitus
  • Functional limitations and disability
  • Infectious diseases including HIV/AIDS
  • Obesity
  • Digestive system conditions (peptic ulcer disease and dyspepsia)
  • Pregnancy including preterm birth
  • Pulmonary disease and asthma
  • Alcohol and drug abuse

View AHRQ Priority Conditions Announcement

Requests for Applications

GrantDetailsDeadlines
NEW Infrastructure Development Program in Patient-Centered Outcomes Research (PCOR) (R24) Supports applications from organizations that propose to improve health outcomes by developing and disseminating evidence-based information to patients, clinicians, policy makers, and health care administrators, responding to their expressed needs about which clinical and health system design interventions are most effective for which patients under specific circumstances. Agencies: AHRQ
PA-12-114
$1,000,000/year, 5 years
Eligibility: Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the PD/PI is invited to work with his/her organization to develop an application for support. A minimum time commitment of 1.8 calendar months (i.e. 15%) annual effort is required from the PD/PI.
Application:
June 19, 2012, Dec 19, 2012, Dec 19, 2013, Dec 19, 2014
NEW Patient-Centered Outcomes Research - Dissemination by Health Professionals Associations (PCOR-DHPA) (R18) Supports health professionals associations to develop dissemination programs that integrate patient-centered outcomes research into clinical practice using innovative methods. These methods could include mechanisms such as education, credentialing, scientific programs, or social media platforms. Applicants may wish to consider both educational theory (what learning methods work most effectively) and the relevance of "new media." Agencies: AHRQ
RFA-HS-12-006
$100,000/year (including F&A costs), 3 years
Eligibility: Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the PD/PI is invited to work with his/her organization to develop an application for support.
Letter of Intent: April 2, 2012
Application:
April 25, 2012
NEW NIH Health Care Systems Research Collaboratory - Coordinating Center (U54) The Coordinating Center will 1) develop, adapt, and adopt technical and policy guidelines and best practices for the effective conduct of research studies in partnership with health care systems; 2) work collaboratively with each Demonstration Project team, including their partnering health care systems, to develop and test an implementation plan for the proposed Demonstration Projects while providing technical, design, and coordination support; and 3) disseminate widely Collaboratory endorsed policies and practices and lessons learned in the Demonstration Projects to inform best practices for broad participation of health care systems and their patients, practitioners, and staff in research studies to improve health and care delivery. Agencies: NCCAM
RFA-RM-11-021
Eligibility: Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support.
Letter of Intent: March 27, 2012
Application:
April 27, 2012
NEW NIH Health Care Systems Research Collaboratory - Pragmatic Clinical Trials Demonstration Projects (UH2/UH3) Awards will initially support a one-year milestone-driven planning phase (UH2), with possible rapid transition to the second implementation phase (UH3) for a pragmatic trial Demonstration Project. Agencies: NIH Health Care Systems (HCS) Research Collaboratory supported through the NIH Common Fund
RFA-RM-12-002
Eligibility: Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support.
Letter of Intent: April 2, 2012
Application:
May 2, 2012

View the complete list of opportunities

Announcements

  • New Methods in Statistical Methodology to decrease potential bias and confounding in Comparative Effectiveness Research — Mark van der Laan, Professor of Biostatistics at UC Berkeley, developed these methods that combine the application of super learning (SL) and targeted maximum likelihood estimation (TMLE). He is looking to apply these methods by partnering with CER researchers and grant applicants with large clinical databases. Learn more.
  • Suspension of Grants Funding Appeals Process

Back to top

UCSF Steering Committee

A Steering Committee charged with coordinating and supporting Comparative Effectiveness Research (CER) at UCSF will meet bi-monthly and may organize a meeting of all faculty interested in CER late fall 2009.

Steering Committee Members >>

  • Co-chair: Deborah Grady, MD, MPH, CTSI Co-Director
  • Co-chair: Clay Johnston, MD, PhD, CTSI Director
  • Lisa Bero, PhD, Professor of Clinical Pharmacy
  • Claire Brindis, DPh, Professor, Institute for Health Policy Studies
  • Ralph Gonzales, MD, Professor of Medicine
  • Dina Halme, PhD, Associate Dean of Special Projects
  • James G. Kahn, MD, MPH, Professor of Health Policy and Epidemiology
  • Michael Kamerick, Director of Academic Research Systems
  • Kathryn Phillips, PhD, Professor of Health Economics and Health Services Research
  • Neil Powe, MD, MPH, MBA, Vice Chair of Medicine, SFGH
  • Joe Selby, MD, MPH, Director, Division of Research, Kaiser Permanente
  • Trainee member: Kendall Allred, MD, MPH, Resident, Emergency Medicine

Stay Informed

Contact us if you would like to be informed of Comparative Effectiveness Research funding opportunities and potential collaborations.

See previous announcements sent to the CER distribution list:

  • April 18, 2012
  • March 12, 2012
  • March 1, 2012
  • February 21, 2012
  • January 31, 2012
  • January 18, 2012
  • December 14, 2011
  • October 14, 2011
  • October 6, 2011
  • September 28, 2011
  • August 12, 2011
  • August 4, 2011
  • May 18, 2011
  • April 18, 2011
  • March 24, 2011
  • March 7, 2011
  • February 28, 2011
  • January 24, 2011
  • January 11, 2011
  • December 3, 2010
  • December 1, 2010
  • November 19, 2010
  • November 2, 2010
  • October 19, 2010
  • September 27, 2010
  • August 16, 2010
  • August 6, 2010
  • July 22, 2010
  • April 6, 2010
  • March 9, 2010
  • February 23, 2010
  • February 17, 2010
  • February 9, 2010
  • January 29, 2010
  • January 22, 2010
  • January 20, 2010
  • January 13, 2010
  • January 7, 2010
  • December 31, 2009 (PDF 32KB)
  • December 17, 2009 (PDF 23KB)
  • December 11, 2009 (PDF 33KB)
  • December 1, 2009 (PDF 34KB)
  • November 3, 2009 (PDF 26KB)
  • October 27, 2009 (PDF 22KB)
  • October 9, 2009 (PDF 26KB)
  • September 24, 2009 (PDF 20KB)
  • September 8, 2009 (PDF 28KB)
  • August 19, 2009 (PDF 12KB)

Back to top

About Comparative Effectiveness Research (CER)

  • Funding Opportunities
  • Resources
  • UCSF Steering Committee

Agency for Healthcare Research and Quality (AHRQ) Effective Health Care Home

What's New

  • View presentations from the First UCSF Comparative Effectiveness Research Symposium: Opportunities and Challenges

CER expertise runs deep at UCSF: Of 182 ARRA grants awarded to UCSF in 2009, 43 are related to CER, accounting for $22.7M of the $62.5M awarded to UCSF. View UCSF project list

See National ARRA Funding Map and Projects

Stay Informed

Join the CER email list if you would like to be notified of Comparative Effectiveness Research funding opportunities and potential collaborations.

See previous announcements

Research Resources

  • Request a Consultation
  • Search Core Facilties
  • UCSF Profiles
  • Clinical Research Services
  • UCSF Participant Recruitment Service
  • Work with Industry
  • Work with Community
  • Informatics Resources
  • mHealth Research Resources
  • Comparative Effectiveness Research
    (CER) Resources
  • Work with Large Datasets
  • Talk to a Research Navigator

Training & Advancement

  • Browse UCSF Opportunities
  • Career Advancement Library
  • Training in Clinical Research (TICR)
  • CTSI Online Education Curriculum
  • Training in Implementation Science
  • Mentor Development Course
  • Clinical and Translational Research (CTR) Fellowship
  • Faculty Opportunities
  • Resident Opportunities
  • Trainee Opportunities

Funding

  • Resource Allocation Program (RAP)
  • K Proposal Library
  • T32 Proposal Library
  • Writing NIH Mentored K Award Applications
  • Faculty Career Development Awards
  • Postdoctoral Funding
  • Resident Funding
  • T1 Translational Catalyst Award
  • Community-Engaged and T2 Funding
  • Comparative Effectiveness Research (CER)
    Funding
  • Informatics Funding

Collaboration Tools

  • UCSF Profiles
  • Open Forums
  • Research Blogs
  • Virtual Meetings
  • Document Collaboration
  • Video on the Web

For Community Partners

  • Request a Consultation
  • Linkage Service
  • Training
  • Collaborative Research Network
  • Working with Researchers
  • Home
  • Site Map
  • Terms of Use
  • non-UCSF Login
  • Contact Us
  • UCSF Login
  • The University of California Copyright © 2012 The Regents of the University of California. All Rights Reserved.

    Services on this website are for the use of UCSF researchers, CTSI affiliates, industry and community members who wish to establish explicit ties to UCSF.

    x

    UCSF Single Sign-On Login

    Login via MyAccess

    Check the box to skip this message on future login

    New to MyAccess?